Rat CTR&RAMP1 UM-UC-3
CBP71663
询 价
索取protocol
产品描述
产品数据库
| I. Background | |
| 大鼠 CTR（降钙素受体）与 RAMP1（受体活性修饰蛋白1）共表达时形成 AMY1 型胰淀素受体家族成员之一。CTR 与 RAMP1 形成的复合物对胰淀素（Amylin）和降钙素基因相关肽（CGRP）均具有高亲和力，顺利获得偶联 Gs 蛋白激活腺苷酸环化酶，增加细胞内 cAMP 水平，参与代谢调控等生理过程。 | |
| II. Description | |
| Rat CTR&RAMP1 UM-UC-3 细胞药靶模型很好的模拟了体内 CTR&RAMP1 的信号转导过程。 |
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III. Introduction |
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| Host Cell: |
UM-UC-3 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
MEM+10%FBS+1% NEAA+ 1mM NaP + 2μg/ml Puromycin + 5μg/ml Blasticidin
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| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for Rat CTR&RAMP1 |
| Transducer: | Gs |
| IV. Representative Data | |
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